I have two blood clotting conditions . Antiphospholipid syndrome and idiopathic thrombocytopenic purpura?

I have two blood clotting conditions .
Antiphospholipid syndrome and idiopathic thrombocytopenic purpura. I was diagnosed with these conditions approx 10-12 years ago after the birth of my 4th child whom I had a normal birth but ended up having an emergency subtotal hysterectomy due to uterine atony . I had to receive 10 pints of blood to due the enormous amount of blood loss . After the birth I developed a pulmonary embolism on my lung due to surgical stockings not being applied and needing bed rest after the traumatic events after giving birth .
My question is could I have acquired any if not both of the blood conditions I have now due to the blood transfusions I received .
I had never had any blood conditions prior to the massive blood transfusion . Plus no problems in previous pregnancies except an emergency c.s with my first child due to her being in distress .

Age: 49
Medications: None
General Information: My itp is mild and I have only ever had one blood clot after childbirth .

2 Comments on “I have two blood clotting conditions . Antiphospholipid syndrome and idiopathic thrombocytopenic purpura?

  1. Blood transfusions are safe. But not without risk. Although donors are screened and blood is tested, risk such as anaphylaxis and contracting blood born diseases still exists. Antiphospholipid syndrome and idiopathic thrombocytopenic purpura are immune disorders and should not be a concern of transmission through blood. Although recipient’s own immune system after blood transfusion is altered for some period of time – it is not known how long nor if there are any consequences. Usually a recipient’s immune system reaction to the donated blood may take from 1 to 14 days. So in short the answer is no this can not have been caused by a blood transfusion you had 10 years ago.

  2. Hi.
    Thanks for the query.

    Antiphospholipid syndrome is an autoimmune hypercoagulable state caused by specific antibodies, and it is known to be associated with the occurrence of blood clots, or thrombosis, in the veins and/or arteries.
    Idiopathic thrombocytopenic purpura is commonly seen in patients with Antiphospholipid syndrome although the exact cause is not known but it can be Immune cause only..

    There are several factors that might trigger the risk of blood clots in antiphospholipid syndrome, including drugs, and there are cases that reported blood clots induced by the drug norethisterone when used by patients with an underlying risk factor for blood clotting. Norethisterone is a drug containing a hormone similar to the progestogen hormone produced naturally in the body. It is used to regulate a number of menstrual cycle disorders, and many women used it to delay their cycles for several days.

    However blood transfusion is not known to cause such diseases and in some cases blood transfusion can even reduce the severity…

    So blood transfusion is probably safe.

    The blood that you are getting transfused make sure is properly investigation before hand so that it is free from any infection etc and is not going to cause any immune reactions..

    Hope this helps..


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